169 research outputs found
Research on Some Phenomenon of E-Government Service Capacity Distribution in Mainland China Based on Multi-channel Perspective
In the context of the government\u27s increasing emphasis on e-government services, this is an urgent need for empirical research of large sample and multi-channels. Therefore, based on the government website, WeChat, Micro-blog, app, by using the existing mature evaluation index system, this paper analyzes e-government service capacity of the city above prefecture- level and provincial. Then, this paper selects the administrative level, economic level, regional balance as the differentiation attribute. It is found that both administrative level and economic level are positively correlated with government service capacity in all the channels. The channel capacity distribution varies related to attribute of administrative and economic, government type of city and province, but it is not restricted by level and region. It provides direction and intensity management to balance and promote channel service capacity for China government
The Influencing Path of Public Engaging Intention in the Value Co-Creation of E-Gov Services:An Empirical Investigation
The wide acceptability of ICTs and social media enriches the delivery platform of e-gov services (EGS). EGS is an important interaction and collaboration channel between the government and the public. The public can conveniently and timely explore problems, provide ideas, and design solutions to improve EGS. The roles of the public changed to active, informed partners or co- creators of EGS innovation and problem solving. This study builds the influence factor model on public engaging intention of value co-creation for EGS based on technology acceptance theory, trust theory, and motivation theory to explore impact factors and impact paths. Path analysis interpreted how the public would accept and adopt value co-creation behavior for EGS. This study also introduced a comprehensive picture of the new paradigm of public service value creation in an era of increasing user dominance, that is, the public
Ultraviolet photon-counting single-pixel imaging
We demonstrate photon-counting single-pixel imaging in the ultraviolet
region. Toward this target, we develop a high-performance compact single-photon
detector based on a 4H-SiC single-photon avalanche diode (SPAD), where a
tailored readout circuit with active hold-off time is designed to restrain
detector noise and operate the SPAD in free-running mode. We use structured
illumination to reconstruct 192192 compressed images at a 4 fps frame
rate. To show the superior capability of ultraviolet characteristics, we use
our single-pixel imaging system to identify and distinguish different
transparent objects under low-intensity irradiation, and image ultraviolet
light sources. The results provide a practical solution for general ultraviolet
imaging applications.Comment: 5 pages, 5 figures, accepted for publication in Applied Physics
Letter
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Calcitonin Receptor Neurons in the Mouse Nucleus Tractus Solitarius Control Energy Balance via the Non-aversive Suppression of Feeding.
To understand hindbrain pathways involved in the control of food intake, we examined roles for calcitonin receptor (CALCR)-containing neurons in the NTS. Ablation of NTS Calcr abrogated the long-term suppression of food intake, but not aversive responses, by CALCR agonists. Similarly, activating CalcrNTS neurons decreased food intake and body weight but (unlike neighboring CckNTS cells) failed to promote aversion, revealing that CalcrNTS neurons mediate a non-aversive suppression of food intake. While both CalcrNTS and CckNTS neurons decreased feeding via projections to the PBN, CckNTS cells activated aversive CGRPPBN cells while CalcrNTS cells activated distinct non-CGRP PBN cells. Hence, CalcrNTS cells suppress feeding via non-aversive, non-CGRP PBN targets. Additionally, silencing CalcrNTS cells blunted food intake suppression by gut peptides and nutrients, increasing food intake and promoting obesity. Hence, CalcrNTS neurons define a hindbrain system that participates in physiological energy balance and suppresses food intake without activating aversive systems
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Photoluminescent Cationic Carbon Dots as efficient Non-Viral Delivery of Plasmid SOX9 and Chondrogenesis of Fibroblasts
With the increasing demand for higher gene carrier performance, a multifunctional vector could immensely simplify gene delivery for disease treatment; nevertheless, the current non- viral vectors lack self-tracking ability. Here, a type of novel, dual-functional cationic carbon dots (CDs), produced through one-step, microwave-assisted pyrolysis of arginine and glucose, have been utilized as both a self-imaging agent and a non-viral gene vector for chondrogenesis from fibroblasts. The cationic CDs could condense the model gene plasmid SOX9 (pSOX9) to form ultra-small (10–30 nm) nanoparticles which possessed several favorable properties, including high solubility, tunable fluorescence, high yield, low cytotoxicity and outstanding biocompatibility. The MTT assay indicated that CDs/pSOX9 nanoparticles had little cytotoxicity against mouse embryonic fibroblasts (MEFs) compared to Lipofectamine2000 and PEI (25 kDa). Importantly, the CDs/pSOX9 nanoparticles with tunable fluorescence not only enabled the intracellular tracking of the nanoparticles, but also could successfully deliver the pSOX9 into MEFs with significantly high efficiency. Furthermore, the CDs/pSOX9 nanoparticles-mediated transfection of MEFs showed obvious chondrogenic differentiation. Altogether, these findings demonstrated that the CDs prepared in this study could serve as a paradigmatic example of the dual-functional reagent for both self-imaging and effective non-viral gene delivery
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